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Sensomic Analysis of Animal-Derived Fragrance Raw Materials (Castoreum, Hyraceum, Beeswax, Civet, Ambergris) – the aim of this doctoral project is to conduct a comprehensive analysis of these fragrance materials using, among others, organic synthesis techniques, GCxGC-MS/MS, GCxGC-MS-O, and LC-MS/MS, combined with an assessment of their toxicity and application properties. The research is planned in collaboration with the Perfume Chemistry team at Université Côte d’Azur in Nice.
Chromatographic, Spectral, and Biological Properties Analysis of Plant Waxes – Currently, commercially available plant waxes do not reflect the full potential of niche raw materials, which are presently treated as waste in the production of concretes (intermediates in the process of obtaining absolutes). The aim of this doctoral research is to conduct a comprehensive analysis of these niche waxes using, among other methods, GCxGC-MS/MS, GCxGC-MS-O, pyGCxGC-MS/MS, and LC-MS/MS, combined with an assessment of toxicity and application properties, including their use in modern cosmetic formulations. The project is planned to be carried out in collaboration with a leading Egyptian producer of natural fragrance and flavor raw materials.
Analysis of the Antimicrobial Properties of Natural Products Against Animal Pathogens. The aim of this doctoral research is to search for complex natural mixtures (NCS) that are active against selected animal pathogens. To achieve this goal, various microbiological and chromatographic techniques will be employed, including GCxGC-MS/MS and LC-MS/MS. The project will be conducted in collaboration with the Faculty of Veterinary Medicine at the Wrocław University of Environmental and Life Sciences.
Molecular and functional characterization of interactions between natural flavor and aroma compounds and proteolytic enzymes. This doctoral thesis will focus on a detailed molecular and functional analysis of interactions between natural flavor and aroma compounds and proteolytic enzymes (proteases). The primary aim of the research will be to determine the influence of these naturally derived substances on the activity, stability, and specificity of proteolytic enzymes, which play a crucial role in biological processes and have significant industrial relevance, particularly in the food, pharmaceutical, and cosmetic industries. Modern analytical techniques will be employed to elucidate interaction mechanisms at the molecular level and to identify potential practical applications resulting from the modulation of enzyme activity by natural aromatic compounds. Thesis will be carried out with cooperation with prof. Marcin Poręba.
Chemoenzymatic synthesis and analysis of the properties of new fragrance compounds using flow chemistry, olfactometry, and combinatorial synthesis techniques.
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