| Research topics |
The proposed research topic is related to the extensive and high impact use of coordination compounds in many areas of our lives. Coordination compounds are used as reagents in analytical chemistry, in hydrometallurgy and extraction, in medical diagnostics and radiochemistry. They participate in the binding of nitrogen and oxygen molecules, photosynthesis, are the components of new materials and biomaterials and are used in disease diagnosis and treatment. As a large group of inorganic drugs, complexes are applied in anti-parasitic, antivirus and anti-cancer therapies.
The aim of the research is to obtain new metal ion coordination compounds with biologically active ligands, which exhibit interesting topological, supra-molecular, self-organizational, spectroscopic, magnetic and biological properties. The development of unique synthesis procedures for the preparation of coordination compounds in crystalline form will be a significant part of the experimental research. Subsequently, the properties of the complexes will be determined by means of X-ray structural analysis, spectroscopic (FT-IR, Raman, NIR-Vis-UV, EPR, HF-EPR) and magnetic methods. The research on complexation reactions of metal ions with ligand systems as well as thermal stability (TG, TGA, DSC), and biological activity tests of the obtained crystalline coordination compounds are carried out in cooperation with other Polish and foreign centers.
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| Keywords |
Bioinorganic chemistry, coordination chemistry, complexes, crystal structure, spectroscopy (FT-IR, Raman, NIR-VIS-UV, EPR, HF-EPR)
potentiometry, spectroscopy (FT-IR, Raman, NIR-VIS-UV, EPR, HF-EPR), magnetic, thermal stability, weak interaction,
antimicrobial activity, cytotoxic and antiproliferative potential
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