| Research topics |
Bioorganic chemistry, medicinal chemistry. Chemistry of peptides and peptidomimetics with dedicated activity. Desgn, synthesis, strructural studies and SAR (structure-activity relationship) studies.
Desing and activity of low-molecular weight inhibitors of several classes of enzymes.
The PhD thesis area, proposed in the coming academic year:
- design, synthesis and activity of peptide conjugates - tyrosinase inhibitors,
- synthesis and mechanism of action of antifreeze glycopeptides (AFGP),
- design, synthesis and activity of inhibitors of the NDM-1 enzyme, responsible for bacterial drug resistance
|
| Keywords |
peptides, peptidomimetics, structure-activity relationship, NMR spectroscopy, synthesis of the peptides, molecular modeling, inhibitor, synthesis
|